Diclofenac Sodium Injection

Description

Diclofenac Sodium Injection IP 75 mg/ml is a nonsteroidal anti-inflammatory drug (NSAID) used for the management of pain and inflammation in various conditions. It provides rapid relief from pain and reduces inflammation.

Uses:

Diclofenac Sodium Injection is primarily used for:

• Pain Relief: Used to manage moderate to severe pain, including postoperative pain, musculoskeletal pain, and pain associated with inflammatory conditions.
• Inflammation Reduction: Helps reduce inflammation in conditions such as arthritis, ankylosing spondylitis, and other musculoskeletal disorders.

Mechanism of Action:

Diclofenac sodium works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are mediators of pain and inflammation. By reducing their production, diclofenac sodium alleviates pain and inflammation.

Benefits:

• Rapid Pain Relief: Provides quick and effective pain relief, particularly in acute conditions.
• Anti-inflammatory Effect: Reduces inflammation, improving mobility and function in affected areas.

Side Effects:

• Common: Nausea, vomiting, abdominal pain, headache, dizziness, and injection site reactions (pain, redness, swelling).
• Less Common: Gastrointestinal bleeding, ulcers, increased blood pressure, liver enzyme abnormalities, and renal impairment.

Precautions:

• Consultation: Consult a healthcare provider before use, especially if you have a history of gastrointestinal disorders, cardiovascular disease, liver or kidney impairment, or any other significant medical conditions.
• Dosage: Follow the prescribed dosage and administration guidelines provided by your healthcare professional. Do not exceed the recommended dose.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medication.
• Avoid Alcohol: Avoid consuming alcohol as it can increase the risk of gastrointestinal side effects.
• Driving and Machinery: Avoid driving or operating heavy machinery if you experience dizziness or drowsiness.
• Drug Interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
• Monitoring: Regular monitoring of liver and kidney function, as well as blood pressure, may be necessary during prolonged use.

Dosage and Administration:

• Administered by a healthcare professional, typically as an intramuscular or intravenous injection.
• The usual dose is 75 mg once or twice daily, depending on the severity of the condition and the patient’s response to treatment.